With the increasing share of wind power, it is expected that wind turbines would provide frequency regulation ancillary service. However, the complex wake effect intensifies the difficulty in controlling wind turbines and evaluating the frequency regulation potential from the wind farm. We propose a novel frequency control scheme for doubly-fed induction generator (DFIG)-based wind turbines, in which the wake effect is considered. The proposed control scheme is developed by incorporating the virtual inertia control and primary frequency control in a holistic way. To facilitate frequency regulation in time-varying operation status, the control gains are adaptively adjusted according to wind turbine operation status in the proposed controller. Besides, different kinds of power reserve control approaches are explicitly investigated. Finally, extensive case studies are conducted and simulation results verify that the frequency behavior is significantly improved via the proposed control scheme.